2006 Heart-Brain summit proceedings
Open heart surgery and
cognitive decline
ARTICLE INTRODUCTION
Mild cognitive decline occurs normally as people age, and specific at-risk populations, such as those with cerebral vascular disease or coronary disease, decline faster. Patients who undergo coronary artery bypass graft surgery(CABG) are known to have an increased risk of stroke, other serious adverse cerebral events, and cognitive decline.
This paper reviews the incidence and the short-term and long-term sequelae of neurologic injury following cardiac surgery. Possible causes of neurologic injury are discussed, as well as strategies for prevention. The potential contributions of genomics in identifying patients at high risk for neurologic injury from surgery are also discussed.
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