2006 Heart-Brain summit proceedings
Hydrocephalus and the heart:
Interactions of the first and third circulations
ARTICLE INTRODUCTION
Chronic hydrocephalus and cardiovascular disease are related, which may result in a dangerous cycle of pathophysiology in elderly patients. Evidence suggests that patients with chronic adult hydrocephalus, also referred to as normal-pressure hydrocephalus, have vascular disease. Studies have shown an increased incidence of arterial hypertension, cardiac disease (including ischemic heart disease, valvular disease, and congestive heart failure), and cerebrovascular atherosclerotic disease in patients with chronic adult hydrocephalus compared with age-matched controls.
A major coordinating factor in the regulation of interactions between the cerebrospinal fluid (CSF) and the cardiovascular system appears to be cardiac impulse control. The CSF spaces of the cranium play a critical role in cardiac impulse absorption by surrounding the cerebral vasculature and controlling blood flow, allowing CSF circulation, when diseased, to reduce blood flow, and CSF manipulation to enhance blood flow. This article briefly reviews proposed mechanisms for interactions between the CSF circulatory system and the cardiovascular system.
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